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ppf · 2021-03-17 08:54:02+00:00

It most certainly is the point. Many other vaccines also do not provide sterilising immunity.

RobertDeNiro | karma 416 | avg karma 2.91 · | 2020-10-26 14:43:18+00:00

There's never been any belief among the scientific community that any of the vaccine candidates would provide sterilizing immunity. That was just a pipe dream.

refurb | karma 27208 | avg karma 1.53 · | 2022-10-03 11:21:51

You’re making a different point.

Vaccines can be sterilizing (preventing infection) or non-sterilizing (reducing disease severity).

Regardless, no vaccine works in 100% of all people who receive it.

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harambae | karma 4907 | avg karma 4.06 · | 2020-11-30 16:30:48+00:00

You're asking if there are vaccines that do not lead to sterilizing immunity? Yes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296151/

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geomark | karma 2866 | avg karma 2.65 · | 2021-11-06 10:29:12

I think because they aren't sterilizing vaccines. They don't prevent infection or transmission. They just reduce severity of the disease.

_-david-_ | karma 2019 | avg karma 1.18 · | 2021-12-02 15:15:06

Are there any vaccines that are actually 100% sterilizing?

ummonk | karma 11811 | avg karma 2.67 · | 2020-11-18 19:33:51+00:00

Note though that it isn't clear at this point to what extent the vaccine confers sterilizing immunity.

mortehu | karma 1857 | avg karma 2.58 · | 2022-01-19 09:48:48

From what I've read, sterilizing immunity from vaccines may simply be a myth, and vaccines thought to have this property don't stand up to scrutiny.

https://www.theatlantic.com/science/archive/2021/09/steriliz...

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valarauko | karma 1046 | avg karma 1.48 · | 2021-05-26 20:13:03+00:00

I think the comment was alluding to 'sterilizing immunity', rather than the aseptic nature of the vaccines themselves.

h2odragon | karma 15145 | avg karma 2.39 · | 2022-08-17 07:55:45

Turns out that vaccines that offer sterilizing immunity are better for public health than those which do not. Who'da thunk it.

bamboozled | karma 7012 | avg karma 1.83 · | 2021-07-13 15:42:48

But you can still infect other people? It's a non-sterilizing vaccine?

rmk | karma 1596 | avg karma 2.01 · | 2021-01-25 03:51:47+00:00

I have been downvoted elsewhere in this thread for saying that it's not clear whether the vaccine confers sterilizing immunity (or perhaps, for suggesting that restrictions will continue until children are vaccinated. Who knows!) Be careful what you say here, lest you get downvoted to oblivion!

cm2187 | karma 24483 | avg karma 3.15 · | 2023-08-28 15:28:11

I understand some vaccines provide sterilizing immunity, others do not. Which is what is causing so much confusion as people are lazily refering to the vaccine "working" or "not working" without specifying what they mean by working.

dragonwriter | karma 118260 | avg karma 2.17 · | 2021-01-06 03:37:33

> They're more likely to work, because they go in the places (your nose) that need to be sterilized.

That doesn't make much sense; vaccines aren't topical treatments for current infections but systemic preparation against future infections.

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tacon | karma 5517 | avg karma 6.29 · | 2022-07-16 22:24:31

"Vaccines are defined as immunogenic preparations of a pathogen that evoke an immune response without causing disease."[1]

"Some vaccines offer full sterilizing immunity, in which infection is prevented completely."[2]

[1] Vaccinology: Principles and Practice (2012), p.3 https://book4you.org/book/2156866/923113

[2] https://en.wikipedia.org/wiki/Vaccine

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beagle3 | karma 16421 | avg karma 2.62 · | 2022-03-07 06:36:40

They are non-sterilizing ; that is, they protect the vaccinee from getting the disease, but not from getting (and shedding) the virus.

We have sterilizing oral ones. They have safety issues, both personal and population level ones.

The essentially perfect way is to give everyone the non-sterilizing one as early as possible in life, and the sterilizing one at a later stage. The non-sterilizing one protects against the safety issues in the sterilizing one.

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tfehring | karma 2700 | avg karma 3.67 · | 2021-09-09 17:08:55

Isn’t the varicella zoster vaccine, which many schools have required for decades, also non-sterilizing?

ppf | karma 736 | avg karma 1.47 · | 2021-03-17 13:21:23

If you really want to nitpick, "what we got" are vaccines that are not known to provide sterilising immunity, and the 3rd party testing that has been done shows limited effect on reducing transmission. That being the case, it would be surprising if they did have sterilising immunity.

zby | karma 2578 | avg karma 2.24 · | 2022-02-04 03:45:23

I tried to google for a list of sterilising and non-sterilising vaccines - but I could not find any. Could you provide sources for your claim that "essentially no viral vaccine prevents infection, with the possible exception of the HPV vaccine"?