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Anectodal I got mine last week, i had some mild discomford in the arm that i got vaccine in, and nothing else.

I am not sure what to make out of latest news about AstraZenica.

Not even sure how much vaccine will help me since I am on biological drugs (that lover the immune response)



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I was stiff in my right leg the day after being vaccinated with AstraZeneca. I could hardly walk, although the effects wore off during the day.

I had zero symptoms too. I mean, I had very mild tenderness in my arm, but that was a symptom of the muscular trauma from the shot itself, not the actual vaccine.

The vaccine appeared to piss off the RSI in my right arm for about two weeks. I would have gotten the shot in my left arm if I knew that was going to happen.

What is so different with AstraZeneca? Should we expect similar side effects with other vaccines?

You received the injection? Can you share some more details, I'm very curious.

Sorry I should point out I had pains even before the first dose but every doctor or specialist I consulted thought they were muscular pains (right chest and shoulder area). So it's likely a vaccine is not the cause but there are so many factors and cofactors to consider it's very hard to make a diagnosis. Other blood tests in March will hopefully clear some of this out --

Thanks for your reply, that’s good to know; I got the Pfizer vaccine by the way (only 1 shot.)

The vaccine symptoms you had were worse than difficulty breathing, losing your smell and taste and fever?! I had a sore arm for a day; what did you have?

addendum: one day after being vaccinated, no issues except the usual sore arm. Go science!

Unfortunately I think any anti inflammatory is not recommended when you get a vaccine. You want the immune system to be fully armed. That is my recollection from googling when I got my vaccines.

Just hang in there you’ll feel better soon.


FTR, most side effects appear (according to what Moderna published so far) only after the booster shot. So IMO you can't tell yet if you were given the vaccine or not.

Not him, but I had arm pain for over a year, under the injection, along with extreme weakness in a particular muscle/motion, from the first shot. I couldn’t sleep on that side at all, and could barely sleep on the other. It eventually went away, but I was terrified it was permanent.

I did not get the boosters. I’ve had people say I’m anti-vax, from this.


> They just started talking about how teenage boys get enlarged heart from it and so forth

Inflammation/swelling of the heart, not enlarging, very rare given the number of shots that have been rolled out, and people recover pretty quickly. Definitely a concern, not a showstopper.

> We did not know this before either, nor did we know about the AstraZeneca's blood clots.

Again, an incredibly low risk and less risk than harm from the virus.

> we just simply have no idea.

This is not really true, we have a ton of data from this vaccine and from previous ones that can inform our expectations.


We have to be careful when comparing the raw numbers. The AstraZeneca vaccine is a vector vaccine and part of it's expected mechanism of action is triggering an (unpleasant) immune response. I'm not sure where the official definition draws the line between side effect and just normal unpleasantness, but I've heard that most people experience symptoms like a mild flu, and pain at the injection site. OTOH I've heard anecdotically that the Pfizer/Biontech vaccine has much less reactions.

Anyway I think we should not lump the mild/expected side effects and the serious and life threatening ones together. Unfortunately it's quite difficult to find reliable numbers for probability of e.g. blood clots after vaccine compared to the general population.

As a physicist, I'd also like to see the probability in the general population, but this population reweighted to match the population that has been given the vaccine. (E.g. if 0.1% of the population are nurses and 2% of the vaccinated are, then multiply their frequency by 20). When I just see a number, I never know how much they take this kind of confounding factors into account.


That is pretty cool. I have so many questions, but you are not obligated to answer ;). How old are you? Did you experience any side effects from the vaccine? Are you a mask wearer? Do you go out in public as others have?

Apparently, since I was an infant, I would get some pretty heavy duty reactions to any vaccine: fever, swelling, being miserable for a few days. As a child, my DPT vaccine was given in the morning and by the afternoon, they had to cut my sleeve off my shirt due to swelling in the arm where I got the injection. As an adult, even the flu vaccine is something I schedule for a Friday because I know that I will be worthless for a few days.

I am two days past my first COVID vaccine dose and still feel lousy, although I can finally lift my arm up ninety degrees now without a lot of pain and the swelling is mostly gone. I'm dreading what Dose #2 will do.

I know, everyone perkily says "That means your immune system has noticed!" but good grief, I often wish they would make vaccine variants without adjuvants.


I had exactly the same reaction to the first dose, except I had muscle pain in the vaccinated arm for 3 days.

Everyone says the second dose is worse although.


It's so strange how that differs so much. I'm not as healthy as you and the vaccine didn't bother me at all. Ok the second time it felt a bit like I had bumped my arm a bit.

Sorry to hear it gets so bad for you though. I understand that makes it a much harder decision.


Which shot did you get? The different vaccines also use different adjuvants (or even none in case of BionTech), so maybe that also plays a role.
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