I'm glad to see that you use PyQt for the GUI. Have you examined PySide as well? It's mostly drop-in compatible with PyQt and has a much better license in my opinion.
PyQt only contains the bindings. You share the same Qt environment across your system (hence qmake needs to be in your path). The python package itself is not that big (~10 MB).
yep. see http://www.riverbankcomputing.com/news/pyqt-496. the pyqt bindings are supported by riverbank, which offers commercial licenses, so they have every incentive to keep it up to date.
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