The question is what use cases can tolerate large throughput hits but not few msec pause times (G1 can also do pauses of a few msec in many cases, I see hundred msec pause times on very large heaps, but not desktop sized heaps).

I suspect there are very few use cases. The G1 team seems to be focusing on scaling to ever larger heaps right now, like hundreds of gigabytes in size. They're relatively uninterested in driving down pause times as Shenandoah is going to provide that for the open source world and Azul already does for the $$$ world.