Guix greatly simplifies things. Like others said for Nix, I really would recommend managing things declaratively in your system config and a manifest file, but the basic cli isn't bad.
guix install ranger
guix remove ranger
guix pull
guix upgrade
guix search ranger
These basics just work how you'd expect last I checked. There is some `guix shell` stuff as well, but I don't use it, so won't be able to say much about it.
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