I will just annotate that with the observation that at the equivalent point (~4 years) into oxycodone's history I doubt it was well known to be addictive. Wiki suggests it was a "Miracle Drug of the 1930s" and they didn't get nervous about it until the 1970s [0].
And I doubt OxyContin came with the liability waivers that I seem to recall the COVID vaccines having.
That is a fairly safe base case - but would you have seen the opioid epidemic coming that resulted in this Supreme Court lawsuit? These things are being proscribed by reasonable doctors as painkillers and appear to have done more rather serious damage.
I will cheekily note that you wouldn't have been following the science if you did, these things were safe, effective, FDA approved and administered by the experts.
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