For their service infrastructure, certainly. Napkin math suggest that they have to sustain peak floods in the ballpark of 500M concurrent clients. Give or take 100M.
However, if you could cripple DNS propagation/resolution from their systems to the next-hop upstreams, it would show up as services being very slow to respond. They do serve content from multiple domains.
I'd be interested to know how Google's 8.8.8.8 infrastructure defends them from DNS level manipulation...
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